2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. Ligands for E3 Ligase Inhibitor

Ligands for E3 Ligase Inhibitor

Ligands for E3 Ligase Isoform Comparison

Ligands for E3 Ligase Inhibitors (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-117937
    BC-1215 1507370-20-8 99.93%
    BC-1215 is a F-box protein 3 (Fbxo3) inhibitor. BC-1215 works by antagonizing of Fbxo3 on TRAF cytokine signaling and exhibits a low IC50 in vitro. BC-1215 can be used for the research of inflammation.
    BC-1215
  • HY-148106
    MEL23 642072-49-9
    MEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription.
    MEL23